Superparamagnetic colloidal flats: A route to studying the non-linear mechanics of actin networks
- Event time: 1:00pm
- Event date: 8th October 2012
- Speaker: Joe Tavacoli (PMMH-ESPCI Paris)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB
A cell's capacity to detect and respond to physical stimuli is largely attributed to actin networks in their cytoskeleton. Consequently, a number of techniques have been developed to study the mechanics of actin networks, including the magnetic chaining of superparamagnetic colloidal beads. Whilst the latter has huge statistical power, it is not well suited to probe, exactly, non-linear responses. In this talk, I will outline a novel method to fabricate superparamagnetic colloidal flats which do allow charachterisation of the non-linear elasticity of actin networks. Further, because the fabrication route controls both the initial pre-field position and the 2D geometry of the flats, I will demonstrate how these factors influence the flats' chaining characteristics under homogeneous magnetic fields.
This is a weekly series of informal talks given primarily by members of the soft condensed matter and statistical mechanics groups, but is also open to members of other groups and external visitors. The aim of the series is to promote discussion and learning of various topics at a level suitable to the broad background of the group. Everyone is welcome to attend..