Brownian ratchet as a model of cell crawling
Statistical Physics and Complexity Group meeting
Brownian ratchet as a model of cell crawling
- Event time: 11:30am
- Event date: 17th October 2012
- Speaker: Elsen Tjhung (Formerly School of Physics & Astronomy, University of Edinburgh)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB
Event details
Some eukaryotic cells (e.g. Keratocyte) are able to crawl on a 2D substrate such as glass slides. This crawling motion is driven by actin filament polymerisation inside the cell. In this talk I will review the Brownian ratchet model to describe cell crawling and in particular I will derive the crawling velocity. References: Peskin CS, Odell GM, Oster G (1993) Biophys. J.; Mogilner A, Oster G (1996) Biophys. J.
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