Brownian ratchet as a model of cell crawling
- Event time: 11:30am
- Event date: 17th October 2012
- Speaker: Elsen Tjhung (Formerly School of Physics & Astronomy, University of Edinburgh)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB
Some eukaryotic cells (e.g. Keratocyte) are able to crawl on a 2D substrate such as glass slides. This crawling motion is driven by actin filament polymerisation inside the cell. In this talk I will review the Brownian ratchet model to describe cell crawling and in particular I will derive the crawling velocity. References: Peskin CS, Odell GM, Oster G (1993) Biophys. J.; Mogilner A, Oster G (1996) Biophys. J.
This is a roughly weekly series of didactical blackboard talks focussing on some theoretical aspect of Condensed Matter, Biological, and Statistical Physics..