Interactions of Short Antimicrobial Peptides with Bacteria
- Event time: 1:00pm
- Event date: 3rd February 2014
- Speaker: Benjamin Little (Formerly School of Physics & Astronomy, University of Edinburgh)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB
In the wake of rising bacterial resistance to 'conventional antibiotics', alternative designs for antimicrobials are being investigated for their potential to fight bacteria. Antimicrobial peptides are a group of molecules that exist broadly in nature, which seem more difficult for bacteria to develop resistance to, but mechanisms of action are not well understood. In order to elucidate some of their mechanisms and interactions, molecular dynamics simulations can be utilised to try and bridge the gap between molecular scale interactions and the effects observed in experiment. In this talk, I will explain some of the set up for these simulations, and the results of some simulations in relation to experimental measurements.
This is a weekly series of informal talks given primarily by members of the soft condensed matter and statistical mechanics groups, but is also open to members of other groups and external visitors. The aim of the series is to promote discussion and learning of various topics at a level suitable to the broad background of the group. Everyone is welcome to attend..