PhD project: The physics of viruses
Viruses are composite nanoparticles (~10 -100 nm diameter) comprising a core of genetic material (DNA or RNA) that is surrounded by thin protein shell (or capsid). Viruses are efficient at transferring their genetic material into a host cell and then hijacking the cell's machinery in order to reproduce. To act as efficient genetic transfer agents, viruses have to exhibit mechanical properties that enable them to withstand the high osmotic pressures of packaged DNA and strong shear flows as they travel around the body.
Potential projects could use:
(A) neutron and x-ray scattering, to relate mechanical response of viruses to structural and dynamical properties of the capsid; or
(B) highly parallelized microfluidics-based experiments (see other project) to investigate virus self-assembly or the influence of phages on bacterial population dynamics.
- Dr Simon Titmuss (School of Physics & Astronomy, University of Edinburgh)
The project supervisor welcomes informal enquiries about this project.
Find out more about this research area
The links below summarise our research in the area(s) relevant to this project:
- Find out more about Physics of Living Matter.
- Find out more about the Institute for Condensed Matter and Complex Systems.
- Find out how to apply for our PhD degrees.
- Find out about fees and funding and studentship opportunities.
- View and complete the application form (on the main University website).
- Find out how to contact us for more information.