PhD project: Using microfluidics to create highly parallelized biological physics experiments
In this project, microfluidics will be used to create arrays of large numbers of monodisperse water-in-oil emulsion droplets, that can be used as picolitre containers in highly parallelized (1e4 replicates compared to 96-well plates of traditional experiments) biological physics experiments. Preliminary experiments investigating the aggregation of proteins, have suggested that the behaviour in these cell-sized containers can be very different from that observed in traditional experiments. In addition to simple protein aggregation experiments, this approach has a lot of potential in investigating how the protein capsid (shell) of a virus self-assembles, and the efficacy of antimicrobial treatments and how bacteria acquire resistance to antimicrobials.
Simple stochastic computer simulations will be used to understand and interpret our experimental results.
The project supervisors welcome informal enquiries about this project.
Find out more about this research area
The links below summarise our research in the area(s) relevant to this project:
- Find out more about Physics of Living Matter.
- Find out more about the Institute for Condensed Matter and Complex Systems.
- Find out how to apply for our PhD degrees.
- Find out about fees and funding and studentship opportunities.
- View and complete the application form (on the main University website).
- Find out how to contact us for more information.