PhD project: Why and How Proteins Stick to Each Other
Ensuring that the right proteins bind to each other is a vital part of building and running healthy cells. But unwanted protein aggregation can be fatal, such as the formation of ‘amyloid fibrils’ in various neurodegenerative diseases (Alzheimer, CJD, etc.) or the clouding of the eye lens in cataracts. Preliminary work suggests that very highly charged proteins may aggregate via a new, generic mechanism. You will use a collection of physical techniques (atomic force microscopy, light scattering, gel electrophoresis, etc.) to study the mechanism of such aggregation and the structure of aggregates formed.
The project supervisors welcome informal enquiries about this project.
Find out more about this research area
The links below summarise our research in the area(s) relevant to this project:
- Find out more about Physics of Living Matter.
- Find out more about the Institute for Condensed Matter and Complex Systems.
- Find out how to apply for our PhD degrees.
- Find out about fees and funding and studentship opportunities.
- View and complete the application form (on the main University website).
- Find out how to contact us for more information.