Kinetics of the Micelle-to-Vesicle Transition
Condensed Matter lunchtime seminar
Kinetics of the Micelle-to-Vesicle Transition
- Event time: 1:00pm
- Event date: 21st August 2000
- Speaker: Jacques Leng (University of Edinburgh)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB
Event details
The equilibrium phase behaviour of lipid-bile salt aqueous mixtures
has been studied to date mainly in biophysical investigations.
A typical phase diagram --- containing micelles, wormlike micelles and
vesicles---appears to be governed by the very different monomer
solubilities and architectures~[1]. However, usual ('equilibrium')
theories fail to predict some main features such as the size of the
vesicles as a function of the lipid concentration. This is why it is
now believed that this transition is mainly governed by its kinetics.
Recent experimental results~[2] show that the vesicle formation indeed proceeds via at least two stages. By dilution of micellar stock solution, elongated micelles rapidly form disc-like micelles which grow much more slowly and finally form vesicles. We present here some preliminary results of a growth kinetics model and the main parameters---electrostatic interactions, fusion processes, etc.---influencing this regime.
[1] Phase Transitions between Vesicles and Micelles Driven by competing Curvatures, Andelman D., Kozlov M., Helfrich W., Euro. Phys. Lett. 25 (3), 1994, pp. 232.
[2] Micelle-to-Vesicle Transition: A Time-Resolved Structural Study, S. U. Egelhaaf, P. Schurtenberger, Phys. Rev. Lett. 82, (1999), p. 2804
Recent experimental results~[2] show that the vesicle formation indeed proceeds via at least two stages. By dilution of micellar stock solution, elongated micelles rapidly form disc-like micelles which grow much more slowly and finally form vesicles. We present here some preliminary results of a growth kinetics model and the main parameters---electrostatic interactions, fusion processes, etc.---influencing this regime.
[1] Phase Transitions between Vesicles and Micelles Driven by competing Curvatures, Andelman D., Kozlov M., Helfrich W., Euro. Phys. Lett. 25 (3), 1994, pp. 232.
[2] Micelle-to-Vesicle Transition: A Time-Resolved Structural Study, S. U. Egelhaaf, P. Schurtenberger, Phys. Rev. Lett. 82, (1999), p. 2804
About Condensed Matter lunchtime seminars
This is a weekly series of informal talks given primarily by members of the institute of condensed matter and complex systems, but is also open to members of other groups and external visitors. The aim of the series is to promote discussion and learning of various topics at a level suitable to the broad background of the group. Everyone is welcome to attend..