Asymmetric exclusion process as a model for protein synthesis
- Event time: 2:00pm
- Event date: 19th February 2010
- Speaker: Luca Ciandrini (University of Edinburgh)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB
Messenger RNA translation is often studied by means of statistical-mechanical models based on the Asymmetric Simple Exclusion Process (ASEP), which considers hopping particles (the ribosomes) on a lattice (the polynucleotide chain). In this seminar, I will first describe the underlying biological process, then I introduce the model and briefly present the known results. In more detail, I use a mean-field approach to study the dynamics of particles associated with an internal stepping cycle. This particular case is biologically relevant since it includes the two fundamental steps of the ribosome's biochemical cycle into the model.
This is a roughly weekly series of didactical blackboard talks focussing on some theoretical aspect of Condensed Matter, Biological, and Statistical Physics..