An Alternative Protein Aggregation Pathway
- Event time: 1:00pm
- Event date: 28th May 2012
- Speaker: Jay Gillam (Formerly School of Physics & Astronomy, University of Edinburgh)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB
The aggregation of protein into amyloid fibrils is implicated in a number of debilitating diseases. We still do not fully understand the role of amyloid in disease, or at what point along the pathway of fibrillation the toxic species occur. A number of proteins have now been shown to have a fibrillation pathway that differs from the typical kinetics and morphology: might this be a toxic pathway?
This is a weekly series of informal talks given primarily by members of the soft condensed matter and statistical mechanics groups, but is also open to members of other groups and external visitors. The aim of the series is to promote discussion and learning of various topics at a level suitable to the broad background of the group. Everyone is welcome to attend..