Super-resolution imaging of rapid biological processes in real-time
- Event time: 1:00pm
- Event date: 25th February 2013
- Speaker: Professor Rory Duncan (Heriot-Watt University)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB
Biochemists have defined a probably complete catalogue of proteins involved in insulin secretion. Similarly, over the last 2 decades, biochemists and physiologists have defined the physical characteristics of different types of ion channels that underlie normal pancreatic beta cell physiology. What is missing is information describing the "wheres and whens": where are these proteins (ie not just for example on the surface of a cell, but how are the single protein molecules arranged) and when do they act? Recently, it has become possible to examine the nano-scale locations, movements and interactions of 1000s of single molecules inside living cells. This talk will present our recent data quantifying the dynamic behaviours of the molecules that catalyse secretion in cells, as well as serve as an advertisement for the Edinburgh Super-resolution imaging consortium (ESRIC), an open-access technology development and instrumentation platform recently funded by the MRC.
This is a weekly series of informal talks given primarily by members of the soft condensed matter and statistical mechanics groups, but is also open to members of other groups and external visitors. The aim of the series is to promote discussion and learning of various topics at a level suitable to the broad background of the group. Everyone is welcome to attend..