Dynamic behaviours during biofilm development
- Event time: 1:00pm
- Event date: 18th January 2016
- Speaker: Munehiro Asally (University of Warwick)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB
Bacterial biofilms offer an attractive model system to study dynamic interactions of cells in a community. At the same time, biofilms are often a clinical challenge due to their extreme tolerance to antibiotics. Combining fluorescence time-lapse imaging, molecular biology, stiffness measurements and mathematical modelling (in collaboration with biologists, physicists and material scientists), we have uncovered physical and metabolic interactions that are crucial for biofilm development. In the first part of my talk, I will present spatio-temporal pattern of cell death and mechanical buckling during biofilm formation of Bacillus subtilis. Then, I will present our recent discovery of oscillatory behaviour of biofilms.
This is a weekly series of informal talks given primarily by members of the soft condensed matter and statistical mechanics groups, but is also open to members of other groups and external visitors. The aim of the series is to promote discussion and learning of various topics at a level suitable to the broad background of the group. Everyone is welcome to attend..