The Gel Phase of OCR, a DNA Mimic
OCR is a protein that imitates the size, shape and charge of a bent piece of DNA. This allows it to perform a vital biological role: disabling a cell's defence against viruses. These physical properties must also be central to the gel phase of OCR. A gel is formed when salt is added to a solution of OCR, a process that causes all other proteins to precipitate. The structure of this gel is unknown and I will be describing a variety of techniques that we are using to investigate it.
This is a weekly series of informal talks given primarily by members of the soft condensed matter and statistical mechanics groups, but is also open to members of other groups and external visitors. The aim of the series is to promote discussion and learning of various topics at a level suitable to the broad background of the group. Everyone is welcome to attend..