How variable is protein production in single cells?

Statistical Physics and Complexity Group meeting

How variable is protein production in single cells?

  • Event time: 2:00pm
  • Event date: 27th November 2009
  • Speaker: Rosalind Allen (Formerly School of Physics & Astronomy, University of Edinburgh)
  • Location: Room 2511,

Event details

Individual bacterial cells can be very different from each other even when they come from the same ancestor. This is (partly) because the processes responsible for making protein from DNA are stochastic. I will attempt to derive expressions for the variance and mean of the number of proteins produced in a cell and show that the variability in protein production is much bigger than for a 'standard' Poisson process.