Structure Formation In Active Networks

Condensed Matter journal club

Structure Formation In Active Networks

  • Event time: 11:30am
  • Event date: 17th June 2011
  • Speaker: Ryan Philips (University of Edinburgh)
  • Location: Room 2511,

Event details


Structure formation and constant reorganization of the actin cytoskeleton are key requirements for the function of living cells. Here we show that a minimal reconstituted system consisting of actin filaments, crosslinking molecules and molecular-motor filaments exhibits a generic mechanism of structure formation, characterized by a broad distribution of cluster sizes. We demonstrate that the growth of the structures depends on the intricate balance between crosslinker-induced stabilization and simultaneous destabilization by molecular motors, a mechanism analogous to nucleation and growth in passive systems. We also show that the intricate interplay between force generation, coarsening and connectivity is responsible for the highly dynamic process of structure formation in this heterogeneous active gel, and that these competing mechanisms result in anomalous transport, reminiscent of intracellular dynamics
Nature Materials 10 462-468 (2011)


Simone Kohler, Volker Schaller, Andreas Bausch

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Given the diversity of research in the CM group, chosen topics vary widely. We tend to stick to high-impact journals - Nature, Science, PNAS and PRL have been popular - but this is not prescriptive..

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