# Brownian ratchet as a model of cell crawling

#### Brownian ratchet as a model of cell crawling

- Event time: 11:30am
- Event date: 17th October 2012
- Speaker: Elsen Tjhung (Formerly School of Physics & Astronomy, University of Edinburgh)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB

### Event details

Some eukaryotic cells (e.g. Keratocyte) are able to crawl on a 2D substrate such as glass slides. This crawling motion is driven by actin filament polymerisation inside the cell. In this talk I will review the Brownian ratchet model to describe cell crawling and in particular I will derive the crawling velocity. References: Peskin CS, Odell GM, Oster G (1993) Biophys. J.; Mogilner A, Oster G (1996) Biophys. J.

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