Stochastic gene expression

Statistical Physics and Complexity Group meeting

Stochastic gene expression

Event details

Gene expression is a fundamentally stochastic process, leading to significant cell-to-cell variations in mRNA and protein levels. When the number of mRNAs and proteins is low, this process cannot be captured by deterministic kinetic models. In this talk I will present a simple stochastic model for gene expression that accounts for experimentally observed temporal bursts in protein numbers, rendering protein number distribution non-Poissonian.