Elucidating the locking mechanism of peptides onto growing amyloid fibrils
Elucidating the locking mechanism of peptides onto growing amyloid fibrils
- Event time: 1:00pm
- Event date: 29th October 2012
- Speaker: Marieke Schor (Formerly School of Physics & Astronomy, University of Edinburgh)
- Location: Room 2511, James Clerk Maxwell Building (JCMB) James Clerk Maxwell Building Peter Guthrie Tait Road Edinburgh EH9 3FD GB
Event details
Amyloid fibrils are highly ordered protein or polypeptide assemblies that are best known in connection with neurodegenerative diseases although more recently a number of naturally occurring fibril-forming proteins with functional rather than disease-related properties have been discovered. In addition, such peptides may be attractive building blocks for self-assembling nanomaterials. We studied the dynamical mechanism of addition of a heptapeptide to a growing fibril though molecular simulations.
About Condensed Matter lunchtime seminars
This is a weekly series of informal talks given primarily by members of the institute of condensed matter and complex systems, but is also open to members of other groups and external visitors. The aim of the series is to promote discussion and learning of various topics at a level suitable to the broad background of the group. Everyone is welcome to attend..